updated Nov 9, 2000

phenotype/ effect	tumors	autocrine transformation C57 or RAC all from Shimizu 1997	paracrine transformation all from Shimizu 1997	increase b-catenin all from Shimizu 1997	duplication axis in Xenopus	somite myogenesis	kidney epithelial induction	axonal remodeling	Neurotrophin-3 expression all from Patapoutian 1999	aggregation cardiac myocytes	Expansion hematopoietic stem cells
gene
Wnt-1	yes Nusse, 1982	yes	yes	yes	yes McMahon,1989	yes Munsterberg 1995 Activates Myf5 Tajbakhsh 1998	yes Kispert 1998	no Lucas 1998			Yes Austin 1997
Wnt-2	yes Roelink 1992	yes	yes	yes	yes Landesman 1997
Wnt-3	yes Roelink 1990	yes	yes	yes		yes Munsterberg 1995	.
Wnt3A	.	yes	yes	yes	yes Wolda 1993		yes Kispert 1998			Yes Toyofuku 2000	Yes Willert 2003
Wnt4	unknown, but see Bradbury 1995.	no	yes no in Shimizu 1997	no	no Ungar 1995	yes Munsterberg 1995 Activates Myf5 and MyoD Tajbakhsh 1998	yes, Herzlinger1994		yes
Wnt-5A	.	no	no	no	no Torres 1996 but yeswith HFz5 He 1997	Activates Myf5 and MyoD Tajbakhsh 1998	no Kispert 1998		no	Yes Toyofuku 2000	Yes Austin 1997
Wnt-5B	.	yes in Wong1994 no in Shimizu 1997	no	no
Wnt-6	.	no in Wong1994 yes in Shimizu 1997	no	no		Activates Myf5 and MyoD. Tajbakhsh 1998
Wnt-7A	.	yes	no	low		no Munsterberg 1995 Activates MyoD Tajbakhsh 1998	yes Kispert 1998	yes Lucas 1998	yes
Wnt-7B	.	yes in Wong1994 no in Shimizu 1997	no	no	yes (J.Brown, Pers. Comm)	no Munsterberg 1995	yes Kispert 1998	yes (Gaston and Salinas, unpublished)	yes
Wnt-8A	.				yes Christian 1993
Wnt-8B	.				yes Cui 1995
Wnt-10B	yes Lee 1995			Yes Ross, 2000							Yes Austin 1997
Wnt-11		yes Christiansen 1996			yes in Ku 1993 no in Du 1995		no Kispert 1998