Blitzer JT, Nusse R.
	A critical role for endocytosis in Wnt signaling. BMC Cell Biol. 2006 Jul 6;7:28. PMID: 16824228 [PubMed - indexed for MEDLINE]

	Gordon MD, Nusse R.
	Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem. 2006 Aug 11;281(32):22429-33. Epub 2006 Jun 22. Review. No abstract available. PMID: 16793760 [PubMed - indexed for MEDLINE]

	Wodarz A, Stewart DB, Nelson WJ, Nusse R.
	Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells. J Cell Sci. 2006 Jun 15;119(Pt 12):2425-34. Epub 2006 May 23. PMID: 16720643 [PubMed - indexed for MEDLINE]

	Ching W, Nusse R.
	A dedicated Wnt secretion factor. Cell. 2006 May 5;125(3):432-3. Review. PMID: 16678089 [PubMed - indexed for MEDLINE]

	Mikels AJ, Nusse R.
	Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 2006 Apr;4(4):e115. Epub 2006 Apr 4. PMID: 16602827 [PubMed - indexed for MEDLINE]

	Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW.
	Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3. Dev Dyn. 2006 Mar;235(3):681-90. PMID: 16425220 [PubMed - indexed for MEDLINE]

	Nusse R.
	Cell biology: relays at the membrane. Nature. 2005 Dec 8;438(7069):747-9. No abstract available. PMID: 16340998 [PubMed - indexed for MEDLINE]

	Povelones M, Nusse R.
	The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling. EMBO J. 2005 Oct 5;24(19):3493-503. Epub 2005 Sep 15. PMID: 16163385 [PubMed - indexed for MEDLINE]

	Gordon MD, Dionne MS, Schneider DS, Nusse R.
	WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature. 2005 Sep 29;437(7059):746-9. Epub 2005 Aug 17. PMID: 16107793 [PubMed - indexed for MEDLINE]

	Povelones M, Howes R, Fish M, Nusse R.
	Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism. Genetics. 2005 Dec;171(4):1643-54. Epub 2005 Aug 5. PMID: 16085697 [PubMed - indexed for MEDLINE]

	Kon C, Cadigan KM, da Silva SL, Nusse R.
	Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila. Genetics. 2005 Apr;169(4):2087-100. Epub 2005 Feb 3. PMID: 15695365 [PubMed - indexed for MEDLINE]

	Marino S, Romelfanger C, Yokota Y, Nusse R.
	Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse. BMC Cancer. 2004 Dec 15;4:91. PMID: 15601467 [PubMed - indexed for MEDLINE]

	Johnson ML, Harnish K, Nusse R, Van Hul W.
	LRP5 and Wnt signaling: a union made for bone. J Bone Miner Res. 2004 Nov;19(11):1749-57. Epub 2004 Aug 23. Review. No abstract available. PMID: 15476573 [PubMed - indexed for MEDLINE]

	Logan CY, Nusse R.
	The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 2004;20:781-810. Review. PMID: 15473860 [PubMed - indexed for MEDLINE]

	Groth AC, Fish M, Nusse R, Calos MP.
	Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics. 2004 Apr;166(4):1775-82. PMID: 15126397 [PubMed - indexed for MEDLINE]

	Galli LM, Willert K, Nusse R, Yablonka-Reuveni Z, Nohno T, Denetclaw W, Burrus LW.
	A proliferative role for Wnt-3a in chick somites. Dev Biol. 2004 May 15;269(2):489-504. PMID: 15110715 [PubMed - indexed for MEDLINE]

	Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, van der Neut R, Spaargaren M, Pals ST.
	Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6122-7. Epub 2004 Apr 5. PMID: 15067127 [PubMed - indexed for MEDLINE]

	Nelson WJ, Nusse R.
	Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 2004 Mar 5;303(5663):1483-7. Review. PMID: 15001769 [PubMed - indexed for MEDLINE]

	Kuhnert F, Davis CR, Wang HT, Chu P, Lee M, Yuan J, Nusse R, Kuo CJ.
	Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):266-71. Epub 2003 Dec 26. PMID: 14695885 [PubMed - indexed for MEDLINE]

	Nusse R.
	Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development. 2003 Nov;130(22):5297-305. Review. PMID: 14530294 [PubMed - indexed for MEDLINE]

	Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ.
	Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science. 2003 Sep 5;301(5638):1391-4. PMID: 12958364 [PubMed - indexed for MEDLINE]

	Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR 3rd, Nusse R.
	Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 2003 May 22;423(6938):448-52. Epub 2003 Apr 27. PMID: 12717451 [PubMed - indexed for MEDLINE]

	Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL.
	A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003 May 22;423(6938):409-14. Epub 2003 Apr 27. PMID: 12717450 [PubMed - indexed for MEDLINE]

	Povelones M, Nusse R.
	Wnt signalling sees spots. Nat Cell Biol. 2002 Nov;4(11):E249-50. No abstract available. PMID: 12415278 [PubMed - indexed for MEDLINE]

	Yamazaki H, Nusse R.
	Identification of DCAP, a drosophila homolog of a glucose transport regulatory complex. Mech Dev. 2002 Nov;119(1):115-9. PMID: 12385759 [PubMed - indexed for MEDLINE]

	Wu CH, Nusse R.
	Ligand receptor interactions in the Wnt signaling pathway in Drosophila. J Biol Chem. 2002 Nov 1;277(44):41762-9. Epub 2002 Aug 29. Erratum in: J Biol Chem. 2005 Sep 2;280(35):31340. PMID: 12205098 [PubMed - indexed for MEDLINE]

	Willert J, Epping M, Pollack JR, Brown PO, Nusse R.
	A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol. 2002 Jul 2;2:8. PMID: 12095419 [PubMed - indexed for MEDLINE]

	Cadigan KM, Jou AD, Nusse R.
	Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless. Development. 2002 Jul;129(14):3393-402. PMID: 12091309 [PubMed - indexed for MEDLINE]

	Penton A, Wodarz A, Nusse R.
	A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics. 2002 Jun;161(2):747-62. PMID: 12072470 [PubMed - indexed for MEDLINE]

	Rulifson EJ, Kim SK, Nusse R.
	Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science. 2002 May 10;296(5570):1118-20. PMID: 12004130 [PubMed - indexed for MEDLINE]

	Kozopas KM, Nusse R.
	Direct flight muscles in Drosophila develop from cells with characteristics of founders and depend on DWnt-2 for their correct patterning. Dev Biol. 2002 Mar 15;243(2):312-25. PMID: 11884040 [PubMed - indexed for MEDLINE]

	Nusse R.
	An ancient cluster of Wnt paralogues. Trends Genet. 2001 Aug;17(8):443. No abstract available. PMID: 11491115 [PubMed - indexed for MEDLINE]

	Wilson SI, Rydstrom A, Trimborn T, Willert K, Nusse R, Jessell TM, Edlund T.
	The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature. 2001 May 17;411(6835):325-30. PMID: 11357137 [PubMed - indexed for MEDLINE]

	Nusse R.
	Developmental biology. Making head or tail of Dickkopf. Nature. 2001 May 17;411(6835):255-6. No abstract available. PMID: 11357114 [PubMed - indexed for MEDLINE]

	Rousset R, Mack JA, Wharton KA Jr, Axelrod JD, Cadigan KM, Fish MP, Nusse R, Scott MP.
	Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Dev. 2001 Mar 15;15(6):658-71. PMID: 11274052 [PubMed - indexed for MEDLINE]

	Roberts RJ, Varmus HE, Ashburner M, Brown PO, Eisen MB, Khosla C, Kirschner M, Nusse R, Scott M, Wold B.
	Information access. Building a "GenBank" of the published literature. Science. 2001 Mar 23;291(5512):2318-9. No abstract available. PMID: 11269300 [PubMed - indexed for MEDLINE]

	Rulifson EJ, Wu CH, Nusse R.
	Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless. Mol Cell. 2000 Jul;6(1):117-26. PMID: 10949033 [PubMed - indexed for MEDLINE]

	Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R.
	Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. 2000 Jul;13(1):15-24. PMID: 10933391 [PubMed - indexed for MEDLINE]

	Bhanot P, Fish M, Jemison JA, Nusse R, Nathans J, Cadigan KM.
	Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development. 1999 Sep;126(18):4175-86. PMID: 10457026 [PubMed - indexed for MEDLINE]

	Willert K, Logan CY, Arora A, Fish M, Nusse R.
	A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development. 1999 Sep;126(18):4165-73. PMID: 10457025 [PubMed - indexed for MEDLINE]

	Willert K, Shibamoto S, Nusse R.
	Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev. 1999 Jul 15;13(14):1768-73. PMID: 10421629 [PubMed - indexed for MEDLINE]

	Hsieh JC, Kodjabachian L, Rebbert ML, Rattner A, Smallwood PM, Samos CH, Nusse R, Dawid IB, Nathans J.
	A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature. 1999 Apr 1;398(6726):431-6. PMID: 10201374 [PubMed - indexed for MEDLINE]

	Millar SE, Willert K, Salinas PC, Roelink H, Nusse R, Sussman DJ, Barsh GS.
	WNT signaling in the control of hair growth and structure. Dev Biol. 1999 Mar 1;207(1):133-49. PMID: 10049570 [PubMed - indexed for MEDLINE]

	Wodarz A, Nusse R.
	Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol. 1998;14:59-88. Review. PMID: 9891778 [PubMed - indexed for MEDLINE]

	Xu YK, Nusse R.
	The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases. Curr Biol. 1998 Jun 4;8(12):R405-6. No abstract available. PMID: 9637908 [PubMed - indexed for MEDLINE]

	Lessing D, Nusse R.
	Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression. Development. 1998 Apr;125(8):1469-76. PMID: 9502727 [PubMed - indexed for MEDLINE]

	Cadigan KM, Fish MP, Rulifson EJ, Nusse R.
	Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell. 1998 May 29;93(5):767-77. PMID: 9630221 [PubMed - indexed for MEDLINE]

	Kozopas KM, Samos CH, Nusse R.
	DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fate. Genes Dev. 1998 Apr 15;12(8):1155-65. PMID: 9553045 [PubMed - indexed for MEDLINE]

	Willert K, Nusse R.
	Beta-catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev. 1998 Feb;8(1):95-102. Review. PMID: 9529612 [PubMed - indexed for MEDLINE]

	Cadigan KM, Nusse R.
	Wnt signaling: a common theme in animal development. Genes Dev. 1997 Dec 15;11(24):3286-305. Review. No abstract available. PMID: 9407023 [PubMed - indexed for MEDLINE]

	Willert K, Brink M, Wodarz A, Varmus H, Nusse R.
	Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J. 1997 Jun 2;16(11):3089-96. PMID: 9214626 [PubMed - indexed for MEDLINE]

	Nusse R.
	A versatile transcriptional effector of Wingless signaling. Cell. 1997 May 2;89(3):321-3. Review. No abstract available. PMID: 9150130 [PubMed - indexed for MEDLINE]

	Cadigan KM, Nusse R.
	wingless signaling in the Drosophila eye and embryonic epidermis. Development. 1996 Sep;122(9):2801-12. PMID: 8787754 [PubMed - indexed for MEDLINE]

	Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew D, Nathans J, Nusse R.
	A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature. 1996 Jul 18;382(6588):225-30. PMID: 8717036 [PubMed - indexed for MEDLINE]

	van Leeuwen F, Samos CH, Nusse R.
	Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells. Nature. 1994 Mar 24;368(6469):342-4. PMID: 8127369 [PubMed - indexed for MEDLINE]

	Noordermeer J, Klingensmith J, Perrimon N, Nusse R.
	dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature. 1994 Jan 6;367(6458):80-3. PMID: 7906389 [PubMed - indexed for MEDLINE]

	Klingensmith J, Nusse R, Perrimon N.
	The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev. 1994 Jan;8(1):118-30. PMID: 8288125 [PubMed - indexed for MEDLINE]

	van den Heuvel M, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R.
	Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J. 1993 Dec 15;12(13):5293-302. Erratum in: EMBO J 1994 Jun 15;13(12):2950. PMID: 8262072 [PubMed - indexed for MEDLINE]

	Salinas PC, Nusse R.
	Regional expression of the Wnt-3 gene in the developing mouse forebrain in relationship to diencephalic neuromeres. Mech Dev. 1992 Dec;39(3):151-60. PMID: 1363370 [PubMed - indexed for MEDLINE]

	Noordermeer J, Johnston P, Rijsewijk F, Nusse R, Lawrence PA.
	The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development. 1992 Nov;116(3):711-9. PMID: 1289061 [PubMed - indexed for MEDLINE]

	Nusse R, Varmus HE.
	Wnt genes. Cell. 1992 Jun 26;69(7):1073-87. Review. No abstract available. PMID: 1617723 [PubMed - indexed for MEDLINE]

	Russell J, Gennissen A, Nusse R.
	Isolation and expression of two novel Wnt/wingless gene homologues in Drosophila. Development. 1992 Jun;115(2):475-85. PMID: 1425336 [PubMed - indexed for MEDLINE]

	Roelink H, Wagenaar E, Nusse R.
	Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors. Oncogene. 1992 Mar;7(3):487-92. PMID: 1549363 [PubMed - indexed for MEDLINE]

	Roelink H, Nusse R.
	Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube. Genes Dev. 1991 Mar;5(3):381-8. PMID: 2001840 [PubMed - indexed for MEDLINE]

	Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H.
	A new nomenclature for int-1 and related genes: the Wnt gene family. Cell. 1991 Jan 25;64(2):231. No abstract available. PMID: 1846319 [PubMed - indexed for MEDLINE]

	Nusse R, Theunissen H, Wagenaar E, Rijsewijk F, Gennissen A, Otte A, Schuuring E, van Ooyen A.
	The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus. Mol Cell Biol. 1990 Aug;10(8):4170-9. PMID: 1695322 [PubMed - indexed for MEDLINE]

Roelink H, Wagenaar E, Lopes da Silva S, Nusse R.

Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4519-23. PMID: 2162045 [PubMed - indexed for MEDLINE]

Rijsewijk F, Schuermann M, Wagenaar E, Parren P, Weigel D, Nusse R. Related Articles, Links The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell. 1987 Aug 14;50(4):649-57.