Graduate courses in Chemical and Systems Biology

The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.

4 units, Win (Ferrell, J; Meyer, T)

CSB 220. Chemistry of Biological Processes

(Same as BIOC 220.) The principles of organic and physical chemistry as applied to biomolecules. Goal is a working knowledge of chemical principles that underlie biological processes, and chemical tools used to study and manipulate biological systems. Prerequisites: organic chemistry and biochemistry, or consent of instructor.

4 units, Spr (Wandless, T; Herschlag, D; Chen, J), alternate years, not given next year

CSB 240A. A Practical Approach to Drug Discovery and Development

Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital.

3 units, Win (Mochly-Rosen, D; Grimes, K)

CSB 240B. A Practical Approach to Drug Discover and Development

(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital.

3 units, Spr (Mochly-Rosen, D; Grimes, K)

CSB 250. The Biology of Chromatin Templated Processes

Topics include mechanisms of DNA replication; gene expressions regulation; DNA damage sensing and DNA repair; chromatin structure and function; and epigenetics and nuclear reprogramming. Prerequisite: working knowledge of molecular biology, biochemistry and genetics, or instructor consent.

4 units, Aut (Cimprich, K; Wysocka, J)

CSB 260. Quantitative Chemical Biology

Current topics including protein and small molecule engineering, cell signaling sensors and modulators, molecular imaging, chemical genetics, combinatorial chemistry, in vitro evolution, and signaling network modeling. Prerequisites: undergraduate organic chemistry, and biochemistry or cell biology.

4 units, Spr (Staff), alternate years, not given this year

CSB 270. Research Seminar

Guest speakers and discussion on current research in pharmacology.

1-2 units, not given this year

CSB 278. Systems Biology

(Same as BIOC 278, BIOE 310, CS 278.) Complex biological behaviors through the integration of computational modeling and molecular biology. Topics: reconstructing biological networks from high-throughput data and knowledge bases. Network properties. Computational modeling of network behaviors at the small and large scale. Using model predictions to guide an experimental program. Robustness, noise, and cellular variation. Prerequisites: background in biology and mathematical analysis.

3 units, Aut (Covert, M; Dill, D; Brutlag, D; Ferrell, J)

CSB 299. Directed Reading in Chemical and Systems Biology

Prerequisite: consent of instructor.

1-18 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

CSB 399. Graduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.

1-18 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

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Stanford Bulletin, Archive 2008-09

Stanford Bulletin, Archive 2008-09

Alphabetical Index

Bulletin Archive

Graduate courses in Chemical and Systems Biology